The San Antonio Campus was established in 1984 as part of Wayland's non-traditional degree programs. The San Antonio Campus moved to its current 30+ acre location in October 2000.

The campus is conveniently located at 11550 IH 35 North and Wayland Way,  one block from  O'Connor Road.   It is easily accessible from the major road networks and is close to Fort Sam Houston, Randolph Air Force Base, and major industrial complexes. 

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